After installing the latest Safari 4.0.3 via Software Update, my Mac suddenly refuses to open new window of Safari. The possible cause of this problem is the plugins that have been installed on your Safari.
The first possible fix is by uninstalling Glims. To do this, you can go to MacHangout FAQ to download Glims Uninstaller.
If Safari is still not working after the installation, you can check on several possible and delete some possible clashing plugins:
Note that you can just: open Finder, hit Cmd-Shift-G, and copy-paste the address written above for quick directory jump.
I have managed to make my Safari working fine now. Hope that you can get your Safari working again too.
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